| Clone ID | DM79 |
|---|---|
| Target | |
| Synonyms | AITR; GITR; TNFRSF18; CD357 |
| Host Species | Rabbit |
| Description | PE-conjugated Anti-GITR antibody(DM79); Rabbit mAb |
| Delivery | Under Development |
| Uniprot ID | Q9Y5U5 |
| IgG type | Rabbit IgG |
| Clonality | Monoclonal |
| Reactivity | Human |
| Applications | Flow Cyt |
| Recommended Dilutions | Flow Cyt 1:100 |
| Purification | Purified from cell culture supernatant by affinity chromatography |
| Formulation & Reconstitution | Liquid,PBS with 0.05% Proclin300, 1% BSA |
| Storage&Shipping | Store at 2°C-8°C for 6 months |
| Background | This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation; and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25( )CD4( ) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |
| Usage | Research use only |
| Conjugate | PE-conjugated |
| DIMA Disclaimer | All DIMA recombinant antibodies are genuinely generated by DIMA Biotech. They are all under patent application. Any protein sequencing or reverse engineering attempt is prohibited. We are actively scr |
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