| Clone ID | DM127 |
|---|---|
| Target | |
| Synonyms | BAFFR;TNFRSF13C;BAFF-R;BROMIX;CD268;CVID4;prolixin |
| Host Species | Rabbit |
| Description | PE-conjugated Anti-BAFF-R antibody(DM127); Rabbit mAb |
| Delivery | Under Development |
| Uniprot ID | Q96RJ3 |
| IgG type | Rabbit IgG |
| Clonality | Monoclonal |
| Reactivity | Human |
| Applications | Flow Cyt |
| Recommended Dilutions | Flow Cyt 1:100 |
| Purification | Purified from cell culture supernatant by affinity chromatography |
| Formulation & Reconstitution | Liquid，PBS with 0.05% Proclin300, 1% BSA |
| Storage&Shipping | Store at 2°C-8°C for 6 months |
| Background | B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also; some SLE patients have increased levels of BAFF in serum. Therefore; it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell surviva |
| Usage | Research use only |
| Conjugate | PE-conjugated |
| DIMA Disclaimer | All DIMA recombinant antibodies are genuinely generated by DIMA Biotech. They are all under patent application. Any protein sequencing or reverse engineering attempt is prohibited. We are actively scr |
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