| Clone ID | DMC464 |
|---|---|
| Target | |
| Synonyms | TL1; VEGI |
| Host Species | Rabbit |
| Description | PE-conjugated Anti-TNFSF15 antibody(DMC464); IgG1 Chimeric mAb |
| Delivery | Under Development |
| Uniprot ID | O95150 |
| IgG type | Rabbit/Human Fc chimeric IgG1 |
| Clonality | Monoclonal |
| Reactivity | Human |
| Applications | Flow Cyt |
| Recommended Dilutions | Flow Cyt 1:100 |
| Purification | Purified from cell culture supernatant by affinity chromatography |
| Formulation & Reconstitution | Liquid，PBS with 0.05% Proclin300, 1% BSA |
| Storage&Shipping | Store at 2°C-8°C for 6 months |
| Background | The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells; but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21:DR6. It can activate NF-kappaB and MAP kinases; and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation; and thus may function as an angiogenesis inhibitor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq; Feb 2011] |
| Usage | Research use only |
| Conjugate | PE-conjugated |
| DIMA Disclaimer | All DIMA recombinant antibodies are genuinely generated by DIMA Biotech. They are all under patent application. Any protein sequencing or reverse engineering attempt is prohibited. We are actively scr |
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