| Clone ID | DMC447 |
|---|---|
| Target | |
| Synonyms | CC-CKR-2; MCP-1-R; CD192 |
| Host Species | Rabbit |
| Description | PE-conjugated Anti-CCR2 antibody(DMC447); IgG1 Chimeric mAb |
| Delivery | Under Development |
| Uniprot ID | P41597 |
| IgG type | Rabbit/Human Fc chimeric IgG1 |
| Clonality | Monoclonal |
| Reactivity | Human |
| Applications | Flow Cyt |
| Recommended Dilutions | Flow Cyt 1:100 |
| Purification | Purified from cell culture supernatant by affinity chromatography |
| Formulation & Reconstitution | Liquid,PBS with 0.05% Proclin300, 1% BSA |
| Storage&Shipping | Store at 2°C-8°C for 6 months |
| Background | The protein encoded by this gene is a receptor for monocyte chemoattractant protein-1; a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The encoded protein mediates agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This protein can also be a coreceptor with CD4 for HIV-1 infection. This gene is located in the chemokine receptor gene cluster region of chromosome 3. |
| Usage | Research use only |
| Conjugate | PE-conjugated |
| DIMA Disclaimer | All DIMA recombinant antibodies are genuinely generated by DIMA Biotech. They are all under patent application. Any protein sequencing or reverse engineering attempt is prohibited. We are actively scr |
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